Second-placed Bournemouth are well on course to secure a return to the Premier League after two years away.
Scott Parker’s side are four points clear of Huddersfield Town in third, while still having two games in hand on the Terriers.
The Cherries have stalled recently; failing to score in their last two outings, including a goalless draw with Sheffield United.
Nevertheless, Bournemouth have been impressive at home, where they are unbeaten in six matches.
The home team has never lost in the 17 previous encounters between the sides in the Football League.
Boro’s play-off hopes have dented following back-to-back defeats, which have left them three points off the top six.
Chris Wilder will look to stop the rot by recording the club’s fourth away win in 34 league games played on Good Friday.
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AFC Bournemouth vs Middlesbrough: Match Stats
Dominic Solanke is Bournemouth’s man of the moment at the Vitality Stadium.
The former Liverpool striker has found the net in each of the Cherries’ last three matches on home soil, while he was also in target in two of their three previous showdowns with Boro.
As for the visitors, they are aiming to avoid suffering three successive league defeats for the first time since February 2020.
AFC Bournemouth vs Middlesbrough: Squawka Says
Scoreline prediction: AFC Bournemouth 1-0 Middlesbrough
December 18, 2021: Middlesbrough 1-0 Bournemouth – Championship
April 2, 2021: Bournemouth 3-1 Middlesbrough – Championship
September 19, 2020: Middlesbrough 1-1 Bournemouth – Championship
October 24, 2017: Bournemouth 3-1 Middlesbrough – League Cup
April 22, 2017: Bournemouth 4-0 Middlesbrough – Premier League
Bournemouth have won each of their last three meetings with Middlesbrough on home soil, although the latter prevailed in the reverse fixture this season.