Five days after their controversial FA Cup third-round tie, the two sides prepare to do battle once more at Villa Park.
United prevailed 1-0 at Old Trafford on Monday, thanks to Scott McTominay’s early header.
Should they take maximum points here, the Ralf Rangnick’s side would become the first team in Premier League history to record 300 away victories.
The Red Devils will fancy their chances at Villa Park; a happy hunting ground for them in recent times.
Indeed, they are unbeaten in their last 22 Premier League visits, last tasting defeat here on the opening day of the 1995-96 season.
Although, Villa came out on top when they collided at Old Trafford back in September, and they are now looking to complete their first league double over United since 1954-55.
But in order to do that, Steven Gerrard’s men must cast aside a poor run of form that has brought four defeats in their last five games.
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Aston Villa vs Man Utd: Match Stats
Statistically, Villa are Cristiano Ronaldo’s favourite opponents in the Premier League.
When the sides have met, the Portugal skipper has been directly involved in 11 goals in nine starts – scoring eight – with both of those tallies the highest he has recorded against a specific opponent.
Meanwhile, his compatriot Bruno Fernandes has taken a penalty in all four of his appearances against Villa in the English top-flight.
We could be on the verge of history as no player or team has ever taken a penalty in five consecutive games against a specific opponent in the competition.
January 10, 2022: Manchester United 1-0 Aston Villa – FA Cup
September 25, 2021: Manchester United 0-1 Aston Villa – Premier League
May 9, 2021: Aston Villa 1-3 Manchester United – Premier League
January 1, 2021: Manchester United 2-1 Aston Villa – Premier League
July 9, 2020: Aston Villa 0-3 Manchester United – Premier League
United have won four of the last five meetings between the sides, while you must go back to October 1999 for their most recent defeat at Villa Park in all competitions.