American Football

Tennessee Titans vs Arizona Cardinals: Predictions, betting trends and stats for Week 1

By Squawka NFL

Published: 22:08, 8 September 2021 | Updated: 15:19, 23 September 2021

The Arizona Cardinals (0-0) are 3-point underdogs heading into their matchup on Sunday, September 12, 2021 against the Tennessee Titans (0-0). The point total is 52.5 for the game.

Titans vs Cardinals predictions

Computer predictions for Titans vs Cardinals
ATS Total Score prediction
Titans (-3) Over (52.5) Titans 28 Cardinals 24

Titans vs Cardinals head-to-head

In the last five matchups between these two squads, Arizona has the edge with a 3-2 record over Tennessee. Tennessee outscored Arizona 112-100 in those five head-to-head matchups.

Titans vs Cardinals betting odds

Titans vs Cardinals Betting Information
Favorite Spread Favorite spread odds Underdog spread odds Total Over total odds Under total odds
Titans -3 -105 -115 52.5 -110 -110

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Titans vs Cardinals betting insights

Titans trends

  • Tennessee had seven wins in 16 games against the spread last year.
  • As 3-point favorites or more, the Titans went 4-5 against the spread last season.
  • Last year, 12 of Tennessee’s 16 games went over the point total.
  • The Titans put up 30.7 points per game last year, 7.8 more than the Cardinals gave up per outing (22.9).
  • Tennessee was 7-5 against the spread and 10-2 overall in games when it recorded over 22.9 points last year.
  • The Titans collected 44.5 more yards per game (396.4) than the Cardinals gave up per matchup (351.9) last season.
  • In games that Tennessee picked up over 351.9 yards last season, the team was 5-6 against the spread and 9-2 overall.

Cardinals trends

  • Arizona beat the spread seven times in 16 games last year.
  • The Cardinals won twice ATS (2-2) as underdogs of 3 points or greater last season.
  • In 16 Arizona games last year, five of them hit the over.
  • The Cardinals put up just 1.8 fewer points per game (25.6) than the Titans gave up (27.4) last season.
  • Arizona was 5-3 against the spread and 6-2 overall in games when it recorded more than 27.4 points last season.
  • The Cardinals averaged just 13.7 fewer yards per game (384.6) than the Titans gave up per matchup (398.3) last year.
  • Arizona was 6-2 against the spread and 7-1 overall when the team picked up more than 398.3 yards last season.

Team stats

Compare 2020 season stats for Titans and Cardinals
Titans Stats Cardinals
239.1 Pass yards 256.4
287.1 Pass yards against 246.8
168.1 Rush yards 139.8
120.8 Rush yards against 125.5
+11 Turnover differential 0

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Player betting tips

Titans top players

  • Bud Dupree boasted an impressive stat line of eight sacks, 11 TFL and 39 tackles last year.
  • In last year’s campaign, Kevin Byard totaled 143 tackles, two TFL, and one interception.
  • Amani Hooker intercepted four passes and tacked on 67 tackles, one TFL, and eight passes defended last season.

Cardinals top players

  • Kyler Murray recorded 3,971 passing yards (248.2 yards per game) with a 67.2% completion percentage last year (375-of-558), while throwing 26 touchdowns and 12 interceptions. He also added 819 rushing yards on 133 carries with 11 touchdowns, averaging 51.2 yards per game.
  • James Conner amassed 721 rushing yards on 169 carries (45.1 yards per game), with six touchdowns on the ground last season.
  • DeAndre Hopkins hauled in 115 passes for 1,407 yards last season with six touchdowns. He was targeted 160 times, and averaged 87.9 yards per game.
  • Christian Kirk added 48 catches for 621 yards and six touchdowns last year. He was targeted 79 times and put up 38.8 receiving yards per game.
  • A.J. Green collected 523 yards on 47 catches with two touchdowns in 2020, averaging 32.7 yards per game (on 104 targets).
  • Dennis Gardeck put together a solid body of work a year ago, notching seven sacks, seven TFL and 18 tackles.
  • Jordan Hicks’ 2020 campaign saw him total 158 tackles, 11.5 TFL, and one interception.
  • Budda Baker intercepted two passes while adding 146 tackles, 8.5 TFL, two sacks, and six passes defended a season ago.


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