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Los Angeles Rams vs Arizona Cardinals: Predictions, betting trends and stats for Week 4

By Squawka NFL

Published: 19:25, 30 September 2021

The Los Angeles Rams (3-0), winners of three straight games, face the Arizona Cardinals (3-0), who are on a three-game winning streak, on Sunday, October 3, 2021 at SoFi Stadium. Los Angeles is a 4.5-point favourite in the game. The over/under is 55 for the outing.

Rams vs Cardinals predictions

Computer predictions for Rams vs Cardinals
ATS Total Score prediction
Cardinals (+4.5) Under (55) Cardinals 29 Rams 25

Rams vs Cardinals head-to-head

Los Angeles holds a 5-0 advantage over Arizona in the past five meetings between these two squads. The Rams have a 2-0 record against the spread in those games against the Cardinals, with the two squads eclipsing the total on one occasion. Los Angeles totaled 152 points in those five matchups compared to Arizona’s 75.

Rams vs Cardinals betting odds

Rams vs Cardinals betting information
Favourite Spread Favourite spread odds Underdog spread odds Total Over total odds Under total odds
Rams -4.5 -110 -110 55 -105 -115

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Rams vs Cardinals betting insights

Rams trends

  • Los Angeles has covered the spread twice over three games with a set spread.
  • In games they have played as 4.5-point favourites or more, the Rams have a perfect ATS record of 1-0.
  • All of Los Angeles’ games have gone over the total this season.
  • The Rams put up 10.0 more points per game (31.7) than the Cardinals give up (21.7).
  • When Los Angeles records more than 21.7 points, it is 2-1 against the spread and 3-0 overall.
  • The Rams rack up 45.3 more yards per game (388.0) than the Cardinals give up per matchup (342.7).
  • Los Angeles is 2-1 against the spread and 3-0 overall when the team totals more than 342.7 yards.

Cardinals trends

  • Arizona has covered the spread two times over three games with a set spread.
  • Arizona’s games have gone over the total once this year.
  • The Cardinals average 13.6 more points per game (34.3) than the Rams surrender (20.7).
  • Arizona is 2-1 against the spread and 3-0 overall in games when it puts up more than 20.7 points.
  • The Cardinals collect 58.3 more yards per game (432.3) than the Rams allow per outing (374.0).
  • In games that Arizona piles up more than 374.0 yards, the team is 2-1 against the spread and 3-0 overall.

Team stats

Compare 2021 season stats for Rams and Cardinals
Rams Stats Cardinals
314.0 Pass yards 335.0
306.7 Pass yards against 227.0
83.7 Rush yards 110.0
92.7 Rush yards against 140.7
+2 Turnover differential +3

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Player betting tips

Rams top players

  • This year Matthew Stafford has 942 passing yards (314.0 yards per game) while going 66-for-94 (70.2%) and tossing nine touchdowns with one interception.
  • Stafford has had a passing touchdown in all three games this year, and multiple passing TDs each time.
  • Darrell Henderson has churned out a team-leading 123 rushing yards (41.0 per game) and two scores. He has added four receptions for 46 yards .
  • Henderson has rushed for a touchdown in two games this season, but did not score more than one in either game.
  • Cooper Kupp has been targeted 33 times and has 25 catches, leading his team with 367 yards (122.3 ypg) while hauling in five touchdowns.
  • Kupp has had a receiving touchdown in all three games he’s played this season, while scoring multiple receiving TDs twice.

Cardinals top players

  • Kyler Murray has 1,005 passing yards (335.0 per game) with a 76.5% completion percentage (78-for-102), throwing for seven touchdowns with four interceptions. He also has 70 rushing yards on 17 carries and three touchdowns.
  • Chase Edmonds has 31 attempts for a team-high 135 rushing yards (45.0 per game) and zero touchdowns. He also has 16 catches for 121 receiving yards .
  • James Conner has 122 yards on 35 carries (40.7 yards per game), with two rushing touchdowns.
  • This year Christian Kirk has 15 catches for a team-high 239 yards (79.7 per game) and two touchdowns.
  • Rondale Moore has tacked on 13 receptions (on 15 targets) for 183 yards and one touchdown.
  • A.J. Green is averaging 60.3 yards per game, with 10 catches for 181 yards and one touchdown.


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