{"id":11730,"date":"2026-09-15T07:12:58","date_gmt":"2026-09-15T11:12:58","guid":{"rendered":"https:\/\/www.squawka.com\/ca\/nfl\/nfl-news\/dolphins-vs-49ers-prediction-picks-odds-week-2\/"},"modified":"2026-09-15T07:12:59","modified_gmt":"2026-09-15T11:12:59","slug":"dolphins-vs-49ers-prediction-picks-odds-week-2","status":"publish","type":"nfl-news","link":"https:\/\/www.squawka.com\/ca\/nfl\/nfl-news\/dolphins-vs-49ers-prediction-picks-odds-week-2\/","title":{"rendered":"Dolphins vs 49ers Prediction, Picks &#038; Odds"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Our <strong>Dolphins vs 49ers prediction<\/strong> is the most one-sided read on the Sunday afternoon card. Squawka Signal&#8217;s live read updates on this page through the week.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <a href=\"https:\/\/www.squawka.com\/ca\/nfl\/teams\/miami-dolphins\/\">Miami Dolphins<\/a> managed 259 yards at Las Vegas and gave up five sacks. The <a href=\"https:\/\/www.squawka.com\/ca\/nfl\/teams\/san-francisco-49ers\/\">San Francisco 49ers<\/a> held the Rams to seven points and scored 27. Week 2 asks Miami to fix the harder of those two problems.<\/p>\n\n\n\n<!-- SQ_NFL_SIGNAL -->\n\n\n\n<style>\n\/* Squawka NFL picks card - palette matched to the injected sq-nsig Signal units *\/\n.sqp{--cy:#2FE6C9;--val:#38D97A;--ovr:#FF6A5A;--fair:#FFC24B;--tx:#e8f0f7;--mut:rgba(232,240,247,.60);--line:rgba(255,255,255,.10);--gold:#FFC24B;position:relative;overflow:hidden;font-family:'Bricolage Grotesque',system-ui,-apple-system,Segoe UI,Roboto,sans-serif;color:var(--tx);max-width:960px;margin:14px auto 26px;border-radius:14px;background:linear-gradient(135deg,#0a2540 0%,#06182b 62%,#04121f 100%);box-shadow:0 14px 36px rgba(4,18,31,.34)}\n.sqp *{box-sizing:border-box}\n.sqp__wrap{padding:22px 26px 20px}\n.sqp__kick{display:inline-flex;align-items:center;gap:8px;font-size:11px;font-weight:800;letter-spacing:.14em;text-transform:uppercase;color:var(--cy)}\n.sqp__kick::before{content:'';width:7px;height:7px;border-radius:50%;background:var(--cy);box-shadow:0 0 9px 1px var(--cy)}\n.sqp__ttl{font-size:24px;font-weight:800;letter-spacing:-.3px;line-height:1.14;margin:12px 0 0;color:var(--tx)}\n.sqp__sub{margin:7px 0 0;font-size:14.5px;line-height:1.5;color:var(--mut);max-width:70ch}\n.sqp__crests{display:flex;align-items:center;gap:10px;margin-top:14px}\n.sqp__crests img{width:28px;height:28px;display:block}\n.sqp__at{font-size:12px;font-weight:700;color:var(--mut);letter-spacing:.1em}\n.sqp__h3{margin:20px 0 0;font-size:10.5px;font-weight:800;letter-spacing:.16em;text-transform:uppercase;color:var(--cy)}\n.sqp__list{margin-top:12px;border-top:1px solid var(--line)}\n.sqp__row{display:grid;grid-template-columns:1fr 126px;gap:14px;align-items:center;padding:14px 2px;border-bottom:1px solid var(--line)}\n.sqp__mkt{display:block;font-size:10px;font-weight:800;letter-spacing:.13em;text-transform:uppercase;color:var(--cy);margin-bottom:4px}\n.sqp__pk{font-size:15.5px;font-weight:800;line-height:1.25;color:var(--tx)}\n.sqp__top{display:inline-block;vertical-align:middle;margin-left:8px;font-size:9.5px;font-weight:800;letter-spacing:.08em;text-transform:uppercase;color:#3a2c00;background:var(--gold);padding:3px 7px;border-radius:5px}\n.sqp__why{display:block;margin-top:5px;font-size:13.5px;line-height:1.5;color:var(--mut)}\n.sqp__pr{text-align:center}\n.sqp__val{display:block;font-size:23px;font-weight:800;color:var(--cy);line-height:1;text-decoration:none}\na.sqp__val:hover{text-decoration:underline}\n.sqp__stars{display:block;font-size:15px;line-height:1;letter-spacing:1px;color:var(--gold)}\n.sqp__stars .d{opacity:.24}\n.sqp__lab{display:block;font-size:10px;letter-spacing:.06em;text-transform:uppercase;color:var(--mut);margin-top:4px}\n.sqp__verd{display:inline-block;margin-top:6px;font-size:10.5px;font-weight:800;letter-spacing:.04em;padding:2px 7px;border-radius:5px}\n.sqp__verd--val{color:var(--val);background:rgba(56,217,122,.12)}\n.sqp__verd--ovr{color:var(--ovr);background:rgba(255,106,90,.12)}\n.sqp__verd--fair{color:var(--fair);background:rgba(255,194,75,.12)}\n.sqp__approach{margin:14px 0 0;font-size:13.5px;line-height:1.55;color:var(--tx)}\n.sqp__foot{margin:16px 0 0;padding-top:13px;border-top:1px solid var(--line);font-size:11.5px;line-height:1.55;color:rgba(232,240,247,.5)}\n.sqp__foot a{color:var(--cy);font-weight:700;text-decoration:none;border-bottom:1px solid rgba(47,230,201,.35)}\n@media(max-width:640px){\n.sqp__wrap{padding:18px 15px 16px}\n.sqp__ttl{font-size:20px}\n.sqp__row{grid-template-columns:1fr 100px;gap:10px}\n.sqp__val{font-size:20px}\n}\n<\/style>\n<div class=\"sqp\" id=\"sqp-miasf\">\n<div class=\"sqp__wrap\">\n<span class=\"sqp__kick\">Week 1 &middot; Editorial pick<\/span>\n<h2 class=\"sqp__ttl\">Dolphins vs 49ers: our editor&#8217;s props<\/h2>\n<p class=\"sqp__sub\">Two editorial calls to sit alongside the live Signal numbers on this page.<\/p>\n<div class=\"sqp__crests\">\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/ca\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/MIA.png\" alt=\"Dolphins\" loading=\"lazy\" width=\"28\" height=\"28\">\n<span class=\"sqp__at\">AT<\/span>\n<img decoding=\"async\" src=\"https:\/\/www.squawka.com\/ca\/wp-content\/themes\/squawka\/inc\/NFL\/assets\/team-logos\/SF.png\" alt=\"49ers\" loading=\"lazy\" width=\"28\" height=\"28\">\n<\/div>\n<h3 class=\"sqp__h3\">Our props<\/h3>\n<div class=\"sqp__list\">\n<div class=\"sqp__row\" data-market=\"Player prop\" data-selection=\"Brock Purdy 2+ passing touchdowns\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Player prop<\/span><span class=\"sqp__pk\">Brock Purdy 2+ passing touchdowns<\/span><span class=\"sqp__why\">Purdy threw three against the Rams at a 105.6 rating. Miami conceded three touchdown passes to Kirk Cousins in Week 1.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 4 of 5\">&#9733;&#9733;&#9733;&#9733;<span class=\"d\">&#9733;<\/span><\/span><span class=\"sqp__lab\">confidence<\/span><\/div>\n<\/div>\n<div class=\"sqp__row\" data-market=\"Team total\" data-selection=\"Miami under 20.5 points\" data-read=\"\">\n<div><span class=\"sqp__mkt\">Team total<\/span><span class=\"sqp__pk\">Miami under 20.5 points<\/span><span class=\"sqp__why\">The Dolphins scored 13 at Las Vegas on 20% third-down conversion. San Francisco conceded seven points to the Rams.<\/span><\/div>\n<div class=\"sqp__pr\"><span class=\"sqp__stars\" role=\"img\" aria-label=\"Confidence 4 of 5\">&#9733;&#9733;&#9733;&#9733;<span class=\"d\">&#9733;<\/span><\/span><span class=\"sqp__lab\">confidence<\/span><\/div>\n<\/div>\n<\/div>\n<p class=\"sqp__foot\">An editorial call, not a Signal model output. 19+ (18+ in AB, MB and QC). Please play responsibly.<\/p>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Dolphins vs 49ers: 2026 form so far<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One side arrives having controlled its opener. The other arrives with a line to repair.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-fixed-layout\">\n<thead>\n<tr>\n<th>2026 season to date<\/th>\n<th class=\"has-text-align-center\" data-align=\"center\">Dolphins<\/th>\n<th class=\"has-text-align-center\" data-align=\"center\">49ers<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr><td><strong>Record<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">0-1<\/td><td class=\"has-text-align-center\" data-align=\"center\">1-0<\/td><\/tr>\n<tr><td><strong>Points for<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">13<\/td><td class=\"has-text-align-center\" data-align=\"center\">27<\/td><\/tr>\n<tr><td><strong>Points against<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">27<\/td><td class=\"has-text-align-center\" data-align=\"center\">7<\/td><\/tr>\n<tr><td><strong>Point differential<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">-14<\/td><td class=\"has-text-align-center\" data-align=\"center\">+20<\/td><\/tr>\n<tr><td><strong>Total yards<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">259<\/td><td class=\"has-text-align-center\" data-align=\"center\">379<\/td><\/tr>\n<tr><td><strong>Yards per play<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">5.2<\/td><td class=\"has-text-align-center\" data-align=\"center\">5.9<\/td><\/tr>\n<tr><td><strong>Turnovers<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">2<\/td><td class=\"has-text-align-center\" data-align=\"center\">1<\/td><\/tr>\n<tr><td><strong>Third-down offence<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">20.0%<\/td><td class=\"has-text-align-center\" data-align=\"center\">58.3%<\/td><\/tr>\n<tr><td><strong>Red-zone offence<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">33.3%<\/td><td class=\"has-text-align-center\" data-align=\"center\">66.7%<\/td><\/tr>\n<tr><td><strong>Sacks recorded<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">0<\/td><td class=\"has-text-align-center\" data-align=\"center\">0<\/td><\/tr>\n<tr><td><strong>Opponent passer rating<\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\">88.2<\/td><td class=\"has-text-align-center\" data-align=\"center\">62.8<\/td><\/tr>\n<\/tbody>\n<\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">San Francisco averaged 5.9 yards a play and gave the ball away once. Miami averaged 5.2 and turned it over twice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dolphins vs 49ers injury report and team news<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Christian McCaffrey carried ten times for 68 yards against the Rams. Brock Purdy finished at a 105.6 rating.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This section updates as soon as the Out, Doubtful and Questionable tags land.<\/p>\n\n\n\n<!-- SQ_NFL_INJURIES -->\n\n\n\n<h2 class=\"wp-block-heading\">The matchup that settles it: Purdy against a secondary Kirk Cousins beat three times<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Miami conceded three touchdown passes at Las Vegas. Purdy threw three of his own against the Rams, which makes the arithmetic uncomfortable.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Malik Willis was sacked five times and threw no touchdowns. San Francisco did not need a single sack to win by 20.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Dolphins&#8217; two interceptions at Las Vegas are the one encouraging note. They will need more than two to stay in this.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Players to watch<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Malik Willis (MIA, QB):<\/strong> 220 yards, no touchdowns and five sacks taken at Las Vegas.<\/li>\n<li><strong>De&#8217;Von Achane (MIA, RB):<\/strong> 11 carries for 36 yards in the opener.<\/li>\n<li><strong>Brock Purdy (SF, QB):<\/strong> Three touchdown passes at a 105.6 rating against the Rams.<\/li>\n<li><strong>Christian McCaffrey (SF, RB):<\/strong> Ten carries for 68 yards at 6.8 a carry.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to watch Dolphins vs 49ers<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The game kicks off at 4:25 PM ET on Sunday, September 20, which is 3:25 PM CT and 1:25 PM PT. CTV has the regional broadcast and RDS the French-language call, and <a href=\"https:\/\/tidd.ly\/3SXLgWO\" rel=\"sponsored nofollow noopener\" target=\"_blank\">DAZN<\/a> carries every game of the season. Squawka may earn a commission if you subscribe through that link.<\/p>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table class=\"has-fixed-layout\">\n<thead>\n<tr><th>Detail<\/th><th>Dolphins vs 49ers<\/th><\/tr>\n<\/thead>\n<tbody>\n<tr><td><strong>Date<\/strong><\/td><td>Sunday, September 20, 2026<\/td><\/tr>\n<tr><td><strong>Kickoff<\/strong><\/td><td>4:25 PM ET \/ 3:25 PM CT \/ 1:25 PM PT<\/td><\/tr>\n<tr><td><strong>Venue<\/strong><\/td><td>Levi&#8217;s Stadium, Santa Clara, CA<\/td><\/tr>\n<tr><td><strong>TV<\/strong><\/td><td>CTV (regional) \/ RDS (French)<\/td><\/tr>\n<tr><td><strong>Live stream<\/strong><\/td><td><a href=\"https:\/\/tidd.ly\/3SXLgWO\" rel=\"sponsored nofollow noopener\" target=\"_blank\">DAZN (NFL Game Pass) \/ CTV.ca<\/a><\/td><\/tr>\n<tr><td><strong>Week<\/strong><\/td><td>Week 2, 2026 NFL season<\/td><\/tr>\n<\/tbody>\n<\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Dolphins vs 49ers prediction and score projection<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Our <strong>Dolphins vs 49ers prediction<\/strong> is a San Francisco win, 27-13. The 49ers control games without straining and Miami cannot protect the quarterback.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Signal&#8217;s live number updates on this page through the week.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Every fixture in the round is covered across our <a href=\"\/ca\/nfl\/\">NFL hub<\/a>, and Signal rates <a href=\"\/ca\/nfl\/picks\/\">every Week 2 game<\/a> the same way. Compare the <a href=\"\/ca\/outright-markets\/afc-championship-odds\/\">AFC Championship odds<\/a> and <a href=\"\/ca\/outright-markets\/nfc-championship-odds\/\">NFC Championship odds<\/a> as the season develops, and our <a href=\"\/ca\/nfl\/nfl-news\/how-to-watch-nfl-in-canada\/\">guide to watching the NFL in Canada<\/a> covers every window.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dolphins vs 49ers FAQ<\/h2>\n\n\n\n<div class=\"schema-faq wp-block-yoast-faq-block\"><div class=\"schema-faq-section\" id=\"faq-miasf-1\"><strong class=\"schema-faq-question\">Who is favoured to win, the Dolphins or the 49ers?<\/strong> <p class=\"schema-faq-answer\">San Francisco, comfortably. The 49ers conceded seven points in Week 1; Miami scored 13.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-miasf-2\"><strong class=\"schema-faq-question\">What time is Dolphins vs 49ers in Canada?<\/strong> <p class=\"schema-faq-answer\">4:25 PM ET on Sunday, September 20, which is 3:25 PM CT and 1:25 PM PT.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-miasf-3\"><strong class=\"schema-faq-question\">What channel is Dolphins vs 49ers on in Canada?<\/strong> <p class=\"schema-faq-answer\">CTV has the regional broadcast and RDS the French. DAZN carries it as a stream.<\/p><\/div><div class=\"schema-faq-section\" id=\"faq-miasf-4\"><strong class=\"schema-faq-question\">How did each side do in Week 1?<\/strong> <p class=\"schema-faq-answer\">Miami lost 27-13 at Las Vegas. San Francisco beat the Rams 27-7.<\/p><\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><em>19+ (18+ in AB, MB and QC) | Please play responsibly | ConnexOntario: 1-866-531-2600 (ON) | Signal probabilities approximate at time of writing and subject to change<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our Dolphins vs 49ers prediction is the most one-sided read on the Sunday afternoon card. Squawka Signal&#8217;s live read updates on this page through the week. The Miami Dolphins managed 259 yards at Las Vegas and gave up five sacks. The San Francisco 49ers held the Rams to seven points and scored 27. Week 2&#8230;<\/p>\n","protected":false},"author":394,"featured_media":11629,"menu_order":0,"template":"","meta":{"_acf_changed":false,"_yoast_wpseo_focuskw":"dolphins vs 49ers prediction","_yoast_wpseo_title":"Dolphins vs 49ers Prediction, Picks & Odds | Squawka","_yoast_wpseo_metadesc":"Our Dolphins vs 49ers prediction, picks and odds for Week 2 at Levi's Stadium. Brock Purdy threw three touchdowns in the opener.","footnotes":""},"tags":[349,328,357],"class_list":["post-11730","nfl-news","type-nfl-news","status-publish","has-post-thumbnail","hentry","tag-miami-dolphins","tag-nfl","tag-san-francisco-49ers"],"acf":{"external_featured_image_url":"","hide_featured_image_pattern":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Dolphins vs 49ers Prediction, Picks &amp; Odds | Squawka<\/title>\n<meta name=\"description\" content=\"Our Dolphins vs 49ers prediction, picks and odds for Week 2 at Levi&#039;s Stadium. 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