Arsenal are approaching their Premier League season opener with a threadbare back-line, due to the absences of Laurent Koscielny, Per Mertesacker and Gabriel.
The former is due to miss the meeting with Liverpool after only arriving back from his summer break this week, following his exploits at Euro 2016.
Meanwhile, Gabriel has been ruled out of action for up to two months through an injury sustained in stoppage-time of last Sunday’s friendly against Manchester City.
Mertesacker – a teammate of Mustafi during Germany’s run to World Cup success in 2014 – is out until the new year with a knee problem.
As such, Arsene Wenger has been forced to accelerate any plans to sign a new centre-back, with Mustafi having been heavily linked to the north London giants this summer.
The Valencia No.5 is now on the verge of a move, according to the Daily Mail.
Mustafi has already accepted a £75,000-per-week contract offer from Arsenal, the source suggests, but a transfer fee is yet to be agreed upon between the two clubs.
However, the report claims that process will be a “formality”, with the Gunners prepared to pay Los Che’s £30m valuation.
That figure would place Mustafi as the fourth-most expensive player in Arsenal’s history, behind Mesut Ozil, Alexis Sanchez and Granit Xhaka.
The 24-year-old, who made more interceptions (133) than any Arsenal player in the league last term, will supposedly pen a five-year deal.